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BIO101L: Introduction to Molecular and Cellular Biology Lab

Unit 8: Cell Division   There are two types of cell division: mitosis, and meiosis.  In this unit, we will study both types, and discover what makes them different from each other.  An understanding of the cell cycle and how division fits into it is emphasized.  The unit begins with a lesson on how to create a “karyotype” (essentially, a photograph of a cell’s chromosomes).  It is important to visually understand the chromosomal content of a cell here, since chromosomal replication and division is an integral part of the cell division process.

Unit 8 Time Advisory
This unit should take you approximately 4 hours to complete.

Unit8 Learning Outcomes
Upon successful completion of this unit, the student will be able to:
- Distinguish between mitosis and meiosis and discuss the significance of each. - List the steps of mitosis and meiosis and identify which step of the process a cell is engaged in. - Design experiments involving your knowledge of what occurs within a cell during different stages of the cell cycle.

  • Interactive Lab: University of Utah: Genetic Science Learning Center’s “Make a Karyotype” Link: University of Utah: Genetic Science Learning Center’s “Make a Karyotype” (Adobe Flash)
     
    Instructions: Before studying the process of cell division, click through this tutorial to learn about what a full “set” of chromosomes is, and how scientists can extract and document a full set of chromosomes from a subject for study.  Think about how creating a subject’s karyotype would be useful in a medical or other scientific study.
     
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8.1 Mitosis   - Web Media: Cells Alive!’s “Cell Cycle” and “Animal Cell Mitosis” and Rutgers University’s “Mitosis Lab” Links: Cells Alive!’s “Cell Cycle”  (Adobe Flash) and “Animal Cell Mitosis” (Adobe Flash) and Rutgers University’s “Mitosis Lab” (HTML)
 
Instructions: Please click through the two tutorials linked above to gain a visual understanding of the process of mitosis.  Be sure that you can remember all of the steps of the process and identify the stage of mitosis by the appearance of the virtual cell.  Then move on to the mitosis lab, where you will see pictures of actual cells undergoing mitosis.
 
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8.2 Meiosis   - Web Media: Cells Alive!’s “Animal Cell Meiosis” and Rutgers University’s “Meiosis Lab” Links: Cells Alive!’s “Animal Cell Meiosis” (Adobe Flash) and Rutgers University’s “Meiosis Lab” (HTML)
 
Instructions: Please click through the Cells Alive! tutorial to gain a visual understanding of the process of meiosis.  Be sure that you can remember all of the steps in the process and identify the stage of meiosis by the appearance of the virtual cell.  Then move on to the mitosis lab, where you will see pictures of actual cells undergoing mitosis, and practice your understanding.
 
Terms of Use: Please respect the copyright and terms of use displayed on the webpage above.

  • Web Media: PBS: NOVA Online’s “How Cells Divide” Link: PBS: NOVA Online’s “How Cells Divide” (Adobe Flash)
     
    Instructions: Please click through this tutorial to gain a visual understanding of the differences between meiosis and mitosis.  The steps of each process will occur concurrently on the screen, allowing you to note the differences.  Then, answer the following questions:
     
    1)    How could you use your knowledge of cell division to understand how best to experimentally inhibit or promote cell growth?
    2)    When might doing this be practically useful?
     
    Check your answers against the Saylor Foundation’s “Answer Guide 8.” (PDF)
     
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